The ability to have children with thalassemia depends on the type of thalassemia in the patient and whether the spouse has the same type of thalassemia. Thalassemia is a hereditary hemolytic anemia. Whether a child can be born has the following conditions: 1. If only one of the spouses has thalassemia, it is possible to have a child, but the child has a half chance of inheriting the thalassemia gene, and the hemoglobin electrophoresis results should be noted after birth. 2. Both husband and wife have thalassemia, especially both have the same type of thalassemia. In this case, there is a high chance of having a child with thalassemia major, genetic counseling is recommended, and if the pregnancy has been confirmed, prenatal diagnosis using genetic analysis is recommended to avoid the birth of a child with hydrops fetalis syndrome or beta thalassemia major. 3. If the mother is a thalassemia major patient, she needs regular blood transfusion for treatment, and abnormalities such as miscarriage or intrauterine growth retardation of the fetus may occur during pregnancy, so it is recommended not to have a child. If you still have questions about having a child with thalassemia, please consult a specialist at a regular hospital.