Radiation stomatitis is the most common complication of head and neck radiotherapy, mainly manifested as: oral mucosal congestion, edema and erosion, leukoplakia formation, ulceration, pain, difficulty in eating, and even affect the normal conduct of radiation therapy and therapeutic effect . According to the World Health Organization can be divided into 4 levels; level 1: mucosal congestion and edema, mild pain; level 2: oral mucosal congestion and edema, punctate ulcers and scattered white film, moderate pain; level 3: oral mucosal congestion and edema, sheet ulcers and fusion of white film, pain and suffering serious and affect the eating; level 4: oral mucosal ulceration of a large area, severe pain, can not eat. I. Prevention of stomatitis 1, teeth cleaning, treatment of gums and oral inflammation before radiotherapy, filling shallow caries, extraction of deep caries and stumps, to be healed (about 10 to 14 days) before starting radiotherapy. 2, patients start radiotherapy from the day, to drink more than 2500ml of water every day, it is best to always have a drinking bottle around, often warm mouth, available honeysuckle, maitake water to drink, so that the oral mucosa moist, in addition to keep the mouth clean, you can self-mixed with some light saline gargle, several times a day, light saline preparation is: in 500ml of warm water, add salt 3 ~ 4g (about half a spoon) can be; Gargle with Doppel liquid for at least 2~4min each time to remove loose tartar. 3.Prevent bleeding after radiotherapy due to increased brittleness of mucosa. Heat-clearing and detoxifying drugs can be taken, such as Liushen Pill and Niu Huang Xieyu Tablet. 4, give high protein, high vitamin, high calorie diet, do not eat too cold, too hot, too hard and fried food, avoid spicy and stimulating food, at the same time to ban smoking and alcohol. 5.Patients should brush their teeth with soft-bristled toothbrush and fluoride toothpaste after each meal, and strengthen mouth rinsing to keep the mouth clean and moist. 6, patients should chew more gum, more chewing exercises, can reduce the difficulty of opening the mouth. Second, stomatitis treatment 1, when the radiation dose of 20GY can appear stomatitis. At this time, patients should be given ultrasonic nebulization inhalation (saline 5ml + Genta 80,000U + chymotrypsin 4000U + dexamethasone 5mg) and local spraying (Vesic or watermelon cream spray or double-digested laryngopharyngeal wind spray) 2 times a day, to anti-inflammatory and pain relief, and to promote the healing of ulcers. 2.Often do open mouth movement, make oral mucous membrane wrinkle wall full contact with fresh air, so as to destroy the growth environment of oral anaerobic bacteria, prevent oral secondary infection. 3, on the oral ulcer pain affects eating, before eating with 0.1% bupivacaine compound vitamin B solution, i.e., compound vitamin B solution 100ml + 2% bupivacaine 5ml, or 1% lidocaine gargle for 2~3min, in order to reduce the pain, increase appetite. Intravenous nutrient supplementation and antibiotics were given to control infection in severe cases.