The results of the 2011 “Chinese Internet Users’ Sexual Well-being Survey” show that nearly 70% of Chinese Internet users are dissatisfied with their sexual well-being. Many patients take an avoidant attitude towards ED. Sexual erectile dysfunction (ED) refers to the persistent inability of the penis to achieve or maintain an erection sufficient for satisfactory sexual intercourse in the past six months. ED is one of the most common sexual dysfunctions in men, and although it is not life-threatening, it can affect the quality of life of both husband and wife, and is also a weathervane of physical health, so it needs attention. The first level of prevention is to eliminate the causes or susceptibility factors of ED. ED and cardiovascular disease have common risk factors, specific measures include: weight loss, smoking and alcohol, low-fat diet and appropriate exercise, maintain a harmonious relationship between husband and wife. Secondary prevention means early detection, diagnosis and treatment, regular screening, regular treatment, and selection of reasonable and effective treatment options. Actively treat primary diseases, such as cardiovascular diseases, hypertension, diabetes and endocrine diseases, evaluate anti-hypertensive drugs, exogenous estrogens, psychotropic drugs, etc., and adjust the dosage and type if necessary to minimize the negative effects of drugs on erectile function. Tertiary prevention refers to measures for patients with refractory ED or severe ED. When PDE5 inhibitors are ineffective or contraindicated, second-line treatments such as intracavernosal injection of vasoactive drugs, intraurethral drug delivery, and vacuum negative pressure devices can be chosen, and surgical treatment can be performed for patients with severe ED for whom other treatments are ineffective, while seeking the understanding and cooperation of partners to improve the quality of life.