Age-related macular degeneration, also known as age-related macular degeneration (AMD), occurs mostly over 45 years of age, and its prevalence increases with age, making it an important disease that causes blindness in middle-aged and elderly people. So far, in modern medicine has not found an exact and effective drug therapy that can stop the progress of the disease. The pathological mechanism of macular degeneration is mainly the aging change of macular region structure. It is mainly due to the decrease of phagocytosis and digestion of the external disc membrane of retinal pigment epithelial cells, so that the undigested disc membrane residual vesicles are retained in the basal cell protoplasm and discharged outside the cells, forming vitreous membrane warts, thus leading to macular degeneration after secondary pathological changes, in short, mainly related to long-term chronic light damage in the macula, choroidal vascular sclerosis and aging of retinal pigment epithelial cells. The disease is divided into two types of clinical manifestations: atrophic type and exudative type: 1, atrophic type is also called dry or non-exudative mainly for choroidal capillary atrophy, vitreous membrane thickening and retinal pigment epithelial atrophy caused by the macular area atrophic degeneration. 2, exudative type also known as wet or disc macular degeneration mainly for the destruction of the vitreous membrane, choroidal vascular invasion into the subretina constitute choroidal neovascularization, the occurrence of macular area retinal pigment subepithelial or neuroepithelial plasma or hemorrhagic disc detachment, and finally become a mechanized scar, according to clinical observation atrophic type can also be transformed into exudative type. Clinical manifestations: 1. The age of onset is above 45 years old, the older the age, the higher the incidence, and the onset is successively in both eyes, which is one of the main eye diseases of visual impairment in the elderly; 2. The central vision decreases slowly, and there may be visual distortion, gaze dark shadow in front of the eyes, and eventually the central vision is lost. The peripheral vision exists; 3. In the early stage of the dry type, pigment disorder in the macula is seen, the central concave reflection is unclear, and there are scattered glass warts. In late onset, there may be metallic reflections in the macula, retinal pigment epithelium atrophy in the shape of a map, and cystic degeneration is seen; 4. Wet type mostly has fused vitreous warts with indistinct borders, dark black graphics in the macula, or irregular lesions, elevation can range from 1-3 PD, large amount of subretinal hemorrhage, which can enter the vitreous, forming a gray-white scar in the lesion area in late vitreous hemorrhage; 5. Fundus fluorescence angiography imaging, presenting translucent fluorescence when showing retinal pigment epithelial atrophy, pigmentation may have obscured fluorescence, early lace-like or reticular neovascularization, and late fluorescein leakage (wet type).