Thigh muscle pain medication depends on the cause of muscle pain, if the lumbar disc herniation and thigh muscle pain, is to treat the lumbar disc herniation, such as absolute bed rest, pelvic traction, local physiotherapy massage, can take oral methylcobalamin tablets, the purpose is to nutritive nerves, to improve the symptoms of the nerve. The second reason is that the surrounding muscles due to chronic pull or acute injury caused by muscle pain, the treatment is mainly to brake, reduce activities, local hot compresses, the use of drugs is mainly to use blood circulation drugs to improve blood circulation, improve the local symptoms.