You can do syphilis spirochete nucleic acid test for syphilis. Syphilis nucleic acid test using PCR method has high sensitivity and specificity, can be used to diagnose syphilis spirochete infection, can be used as a screening and quantitative test to observe the efficacy of treatment, relapse and re-infection. Diagnosis of syphilis can also be carried out such as syphilis serologic testing. Suspects can be tested for syphilis through antigen and antibody testing, and judgment can be made based on the results of these tests. Syphilis spirochetes can be found in mucous membranes or skin lesions by immunofluorescence or dark-field microscopy. It is recommended that people with syphilis or high-risk sexual behaviors seek medical attention for a definitive diagnosis and standardized treatment.