There is no one better than the sartans and prilosec, they are designed for different individuals and have a good effect on lowering blood pressure. It is recommended to use the medication under the supervision of a doctor, and their medication regimens differ for different conditions. Sartans have an effect on angiotensin receptors and it is more direct in lowering blood pressure. Prilosec antihypertensive drugs can not only inhibit angiotensin, but also inhibit the decomposition of bradykinin, which has the effect of lowering blood pressure. Some patients taking Prilosec may have adverse reactions such as dry cough and angioedema. For patients with renal insufficiency, if the creatinine level is more than 2.5mg/day L, then the use of Prilosec antihypertensive drugs is not recommended. Patients taking sartan-type antihypertensive drugs generally do not have the side effects of dry cough and angioedema adverse effects, and can also be taken with creatinine levels below 3mg/dL. Which blood pressure lowering medication is better has different benefits for different hypertensive patients. Patients also need to choose the right antihypertensive medication based on their age and fitness level, body type, and as prescribed by their doctor.