In addition to the above treatment modalities, treatment of the prostate includes experimental local therapies such as cryotherapy, high-energy focused ultrasound, and radiofrequency ablation of intra-tissue tumors. More long-term clinical studies are needed to evaluate the effectiveness of these experimental local treatment modalities for clinically limited prostate cancer compared to radical prostatectomy and radical radiotherapy. Cryotherapy for prostate cancer is free of radiological risks and has a low rate of rectal injury. Common complications include erectile dysfunction, tissue loss, urinary incontinence, and pelvic pain. High-energy ultrasound (HIFU) uses ultrasound generators such as piezoelectric crystals or acoustic lenses to emit high-energy ultrasound waves outside the body and focus the ultrasound energy within the body on selected areas of organ tissue. Radiofrequency ablation of intra-tissue tumors (RITA) is to pierce needle-like electrodes directly into the tumor site and transmit high-power radiofrequency energy through the ablation electrodes to the tumor tissue through the radiofrequency ablation instrument measurement and control unit and computer control, using heat to produce coagulative necrosis of the tumor tissue.