When men’s scrotum is moist and a little itchy, it may be due to scrotal eczema, chronic prostatitis, fungal infections and other diseases, giving general treatment, medication and other programs. 1. Scrotal eczema: this disease may be due to infection, endocrine disorders and other factors. Its clinical symptoms are mostly characterized by local itching, redness and swelling of the skin. Patients can follow the doctor’s instructions to use hydrocortisone cream, dexamethasone cream and other drugs for treatment. 2. Chronic prostatitis: it is usually a chronic inflammatory lesion caused by pathogenic microbial infection and urinary reflux. Inflammatory media stimulation may cause the patient to appear scrotal moisture, and accompanied by itching phenomenon. Patients can use levofloxacin, azithromycin and other drugs for treatment. 3. Fungal infection: the scrotum and thigh area is close, in daily life do not pay attention to personal hygiene or long-term sweating, may lead to fungal infections, thus appearing scrotum moisture and a little itchy phenomenon. Patients can use ketoconazole cream, clotrimazole cream and other drugs for treatment. To summarize, male scrotum moisture and a little itchy, may also be related to the quality of underwear and other factors, it is recommended that timely medical examination, to avoid delaying the condition, resulting in adverse consequences.