The treatment of severe insomnia includes two aspects: 1. Medication. In clinical practice, the most used sleeping drugs are non-benzodiazepines, that is, dezopiclone, zopiclone, zaleplon, zolpidem, etc. If this type of medication does not provide complete improvement of the patient’s insomnia, in clinical practice, antidepressants with sleep improving effects, such as clozapine, trazodone, amitriptyline, doxepin, etc., are also used. The doctor needs to consider the patient’s gender, age, physical illness and previous medications to choose which drug to use.2. In addition to the above medications, cognitive behavioral therapy is also needed for patients with insomnia. Patients with insomnia are often overly concerned about the consequences of sleep, and also exaggerate the idea that insomnia can have serious consequences. First, it is important to give patients a correct understanding of the dangers of insomnia and teach them ways to adjust their sleep so that they can sleep better only if they reduce their fear of insomnia. Good sleep hygiene habits, such as not staying in bed, not catching up on sleep, and not lying in bed waiting for sleep, are also helpful for the improvement of insomnia. In addition, the need for proper aerobic exercise, aerobic exercise is also helpful for the improvement of sleep.