No food can lower the number of white blood cells in the peripheral blood. If a person has an abnormally high number of white blood cells in the peripheral blood, it is rarely lowered by food, and in most cases oral medications are needed to lower the white blood cell count. There are various drugs commonly used in clinical practice to lower leukocytes, such as hydroxyurea, a cell cycle non-specific drug. It can be applied to elevated white blood cell counts caused by various conditions, such as chronic granulocytic leukemia and acute granulocytic leukemia. By taking hydroxyurea it is able to lower the white blood cell count, but it also lowers the red blood cell and platelet count at the same time. Therefore, it is important to have regular blood tests while taking hydroxyurea and adjust the dosage of hydroxyurea according to the results of the blood tests. In addition to hydroxyurea, chemotherapy drugs such as cyclophosphamide and methotrexate can also be taken orally to lower the white blood cell count. However, these drugs are oral chemotherapeutic drugs and require specialized physicians to guide patients in their administration. In clinical work, the cause of high white blood cells needs to be clarified in order to prescribe the right medication.