C-reactive protein is not always high in rheumatoid arthritis patients, and it is related to the changes of the disease. Generally, C-reactive protein will be elevated in the acute active period; if the disease is in remission, C-reactive protein may be within the normal range. C-reactive protein, or CRP, is commonly used to detect the presence of infection, cardiovascular disease, systemic lupus erythematosus, rheumatoid arthritis and other conditions, in which rheumatoid arthritis patients with elevated C-reactive protein usually suggests that the patient is in the active phase of rheumatoid arthritis disease, C-reactive protein value can usually be normalized after the patient’s condition is in remission. If C-reactive protein is elevated again during the recovery process of rheumatoid arthritis, it suggests that the patient may have clinical symptoms again. Therefore, although C-reactive protein is not a specific laboratory indicator for rheumatoid arthritis, C-reactive protein can be detected to observe the patient’s condition and adjust the treatment program in a timely manner. Laboratory test results should be interpreted by a professional physician, and it is recommended that rheumatoid arthritis patients go to the rheumatology and immunology department of a regular hospital for detailed consultation.