In diabetic foot, the lower extremity vascular permeability is reduced due to high sugar, which leads to ischemia and hypoxia in the lower extremity soft tissues. In this condition for a long time, first of all, the soft tissues become necrotic and form ulcers, the nerves in the lower limbs become damaged, and the sensory ability decreases to different degrees. If not treated for a long time, or if trauma occurs and one does not feel it, the wound does not heal easily and gradually ulcerates, which seriously affects the quality of life of the patient. Professor Wang Jiangning, Vice President of Capital Medical University, was the first person to introduce “maggot bio-clearing therapy” into China. Through continuous exploration of bio-clearing therapy, he successfully applied bio-clearing therapy to the treatment of severe infection and ulceration of diabetic foot, and achieved very remarkable achievements. It has been well received by experts at home and abroad and has saved countless patients from amputation and preserved limb function! Medical maggots can enter deep wounds that are difficult to reach by surgery, and can stimulate the growth of granulation through constant crawling and peristaltic movement, and the maggots themselves will secrete a fluid, and this secretion has been studied to be stronger and more stable than penicillin and cephalosporin III in its bactericidal and anti-infective effects. This is why maggots are able to survive in highly decomposed soft tissue and feces. The treatment is more effective than conventional methods in removing wound flesh and accelerating the healing of ulcerated wounds, thus preventing patients from undergoing amputation due to limb ulceration. In the 1940s, the advent of antibiotics caused maggot therapy to be abandoned, and the use of maggots to treat disease became a crude and unscientific native method. In the United States and some European countries maggot therapy is widely used for various septic infections of wounds, including: abscesses, burns, gangrene and chronic leg ulcers, with good clinical results and a clinical treatment rate of 80%. Professor Wang Jiangning also said that because of the different cultures at home and abroad, maggots have long been integrated into people’s daily life and there is no rejection of maggot therapy treatment. However, in China, the application of maggot therapy is confined by traditional concepts, and most of them express fear and rejection of such worm treatment. Still, people will accept this treatment when they really face amputation and death. But this is too passive and not only affects the treatment, but also restricts the development of this technology in China. If maggots are widely used in China, then our medical level will take a big step forward, further promoting wound healing, protecting preserved limbs and preserving lives!