Children with precocious puberty are likely to have premature bone development and early epiphyseal closure before they reach developmental age, resulting in a generally short adult size. The epiphysis is the center of secondary ossification that occurs at different times after birth, and the epiphysis and epiphyseal plate are the growth areas of the immature long bones of the limbs, which are also the weakest and most fracture-prone parts of the bones of children. General X-ray fluoroscopy can confirm whether the epiphysis closes prematurely. Diagnostic tests for precocious puberty: A detailed and complete medical history and include the development of sexual characteristics, vaginal bleeding, and the presence of endocrine medication. Measurement of follicle stimulating hormone FSH and LH by radioimmunoassay can help to differentiate between true and false precocious puberty. In cases of somatic precocious puberty, there may be enlarged ovaries and cystic changes. If adrenocortical disorders are suspected, retroperitoneal inflatable imaging may be performed. The frontal and lateral images of the skull, the size of the butterfly saddle can be observed to exclude tumors, etc. 1. plasma FSH and LH determination. 2. bone age determination. 3. ultrasound examination. 4. CT or MRI examination. 5. other examinations: further choices can be made according to the clinical manifestations of the child.