Hippocampal sclerosis is a specific pathological manifestation of the hippocampus of the brain tissue, which can lead to structural changes in the hippocampus. It also leads to necrosis of brain cells and affects the excitability between cells, which can produce abnormal cell discharges. Generally, patients can have seizures, which can be accompanied by mental symptoms, such as memory loss and slow reaction. For hippocampal sclerosis, there is no particularly effective drug treatment. At present, hippocampal sclerosis is considered to be related to genetics and high fever and convulsions during childhood, and patients can be given neurological examination if necessary. Some patients with hippocampal sclerosis may have tumors, which can usually be detected by CT or MRI of the head. For hippocampal sclerosis, it is recommended that patients should develop good habits and avoid anxiety and fire or bright light stimulation.