Hepatitis B virus DNA quantification is less than 20IU/mL, indicating that the current hepatitis B virus DNA is negative, the body can not detect hepatitis B virus viral replication, and the virus is low infectious. Hepatitis B virus DNA quantification can reflect the active degree of replication of hepatitis B virus in the organism, and indicate the strength of hepatitis B virus infectiousness. When the quantification of hepatitis B virus DNA is less than 20IU/mL, it indicates that the body has better control of the hepatitis B virus or is not infected with the hepatitis B virus, and the viral replication ability is low, so the body has low viral contagiousness. If you are currently undergoing anti-hepatitis B virus treatment, you can continue with the original anti-virus treatment program with better results. Hepatitis B virus DNA quantification less than 20IU/mL can not exclude the possibility of negative infection with hepatitis B virus, and should be combined with other indicators to determine.