Uric acid 448μmol/L is higher than the upper limit of the normal reference range and is considered high. Normal human blood uric acid level is 89~357μmol/L for women and 150~416μmol/L for men. Male or female patients with blood uric acid 448μmol/L are higher than the upper limit of the normal reference range, may be hyperuricemia, heredity, disease, drugs and excessive production of organic acids can lead to purine metabolism disorders and uric acid excretion disorders, the emergence of elevated uric acid. Patients can control uric acid levels through dietary management and improved lifestyle habits, and should receive medication if necessary. Patients with high uric acid level should avoid eating animal foods with high purine content such as liver, kidney, seafood and broth, avoid smoking, drinking alcohol, do aerobic exercise, and review the blood uric acid level regularly and follow the prescribed treatment. Laboratory test results should be interpreted by a professional physician, it is recommended that patients with a blood uric acid level of 448 μmol/L go to the Endocrinology Department, Rheumatology and Immunology Department of regular hospitals and other related departments for detailed consultation.