Toothache may lead to facial swelling. There are various gaps in the face that are connected to the inside of the mouth, and common ones include infection of the occlusal space and infection of the submandibular space, which means that facial swelling can occur. Spreading of inflammation can occur when a mandibular molar has periapical inflammation, an alveolar abscess, or a mandibular wisdom tooth has a pericoronal abscess that is not controlled in a timely manner. Since the biting muscle and the lateral bone wall of the mandibular branch form the occlusal space, it is particularly susceptible to occlusal space infection, which manifests as swelling and pain centered on the angle of the mandible. Submandibular space infections often begin with a history of toothache, followed by swelling of the mandibular lymph nodes and, over time, swelling and pain in the submandibular triangle. A toothache can lead to facial swelling and a visit to your local dentist is recommended.