An explosive fracture of the thoracic 12 is a burst fracture of the thoracic 12 vertebrae, which is more likely to compress the nerves when turning over. The thoracic 12 vertebra is located where the thoracic spine connects to the lumbar spine, so turning over or bending over usually requires the thoracic 12 vertebra to coordinate movement. If an explosive fracture occurs in this area, then compression of the nerves may occur when turning over. When a burst fracture of the thoracic 12 vertebra occurs, internal fixation is usually performed surgically. If necessary, a laminectomy should also be performed to decompress and relieve the nerve compression. Secondly, do not take it lightly after the surgery, but use nutritive nerve medications, such as nerve growth factor and methylcobalamin, under the guidance of your doctor. Thoracic 12 vertebra burst fracture has a great impact on the patient’s health and life, and may even cause paralysis of the lower limbs. Therefore, we should pay attention to it, actively treat it and take care of it scientifically.