Headache and nausea can be treated with Bullo, indomethacin and naproxen, as well as acetaminophen. Vitamin B6 and metoclopramide can also be taken if the patient has severe nausea, and the etiology should also be analyzed for appropriate treatment to cause headache and nausea, including primary and secondary headache. Primary headache disorders, mainly seen in tension headaches, are mainly treated with symptomatic pain relief. Common causes of secondary headache include such as brain tumors, cerebrovascular diseases, mainly seen in massive cerebral infarction, cerebral hemorrhage and subarachnoid hemorrhage. They may also occur if the patient has a central nervous system infection. Patients with cerebral hemorrhage should be promptly hospitalized for comprehensive treatment, including surgical treatment and conservative treatment. Patients with cerebral infarction include thrombolytic therapy and oral aspirin antiplatelet aggregation therapy, as well as neuroprotective therapy and treatment to improve blood circulation. If the patient has elevated blood pressure, which may also occur, oral amlodipine and irbesartan can be administered to lower blood pressure.