Is smoker’s disease serious and is it hereditary? Smoker’s disease is a lesion of the cerebral vessels, the terminal internal carotid artery, the anterior cerebral artery, the middle cerebral artery, and sometimes the posterior cerebral artery, that causes chronic progressive narrowing or occlusion, followed by the formation of a smoky network of small malformed vessels at the base of the skull. Regarding the cause of the formation of smog, some scholars believe that it may be genetically related, while most believe that it is an acquired occlusive cerebrovascular disease. As a rare disease, the incidence of smog is relatively low, but the damage is very serious. Experts say that since the prevalence of smog is mainly in children under the age of ten and adults around the age of forty, the risk is divided into two parts. Most children with smog are ischemic, and often suffer from headache, dizziness, weakness of limbs, unfavorable movement, numbness, speech impairment, blurred vision, visual field loss, etc. Most adults with smog are hemorrhagic, and usually suffer from severe headache, dizziness, impaired movement of limbs, cerebral infarction and cerebral hemorrhage, etc. Therefore, it is very dangerous to suffer from smog and must be treated in time. It is very dangerous and should be treated promptly. For the treatment of smog, there are mainly conservative treatment, direct vascular bypass surgery, indirect vascular bypass surgery, and combined vascular bypass surgery in clinical practice. The medical community generally believes that conservative treatment is not very useful for smog, and direct bypass or indirect bypass surgery has certain limitations and defects, such as limited improvement of blood supply by direct bypass and slow onset of indirect bypass. Among these treatment modalities, combined vascular bypass surgery is currently a very effective procedure for the treatment of smog. While direct bypass rapidly improves the blood supply to the main vessels, extensive multifactorial patching of the brain surface is performed to induce neovascularization and expand the scope of blood supply improvement, which can have a very good effect on the treatment of smog patients.