According to the TNM staging system, pancreatic cancer with a diameter of 2.5cm may be stage IB, IIB, III or IV. Pancreatic cancer staging needs to be evaluated by integrating three indicators: primary tumor (T), regional lymph nodes (N) and distant metastasis (M).A 2.5cm tumor belongs to T2 in the indicator of primary tumor. If there are no regional lymph nodes and distant metastases, it belongs to stage IB according to TNM staging; if the number of lymph node metastases is within three and there are no distant metastases, it is stage IIB; if the number of lymph node metastases is at least four and there are no distant metastases, it is stage III; and if there are distant metastases, it is stage IV, regardless of whether there are lymph node metastases or not. Pancreatic cancer has a high degree of malignancy and poor therapeutic effect, so it is recommended to go to regular hospitals to evaluate the condition, follow the doctor’s instructions to cooperate with the treatment, and choose the appropriate treatment plan to prolong the survival period and improve the quality of life.