Normal people are not prone to nephritis, but the incidence of nephritis is still higher in patients with underlying pathologies and immune deficiencies. Glomerulonephritis is a disease in which autoimmunity is involved, with symptoms such as swelling of both lower limbs and elevated blood pressure. A normal person with normal immunity and no underlying pathology such as hypertension, diabetes, or connective tissue disease is not prone to glomerulonephritis at this time. If a patient with diabetes, hypertension, connective tissue disease and other diseases, such patients are more likely to get nephritis because of their low immunity and long-term lesions that can cause secondary kidney damage and inflammation. Normal people should usually pay attention to strengthening exercise, living a regular life, avoid staying up late, etc., so as to enhance physical fitness, strengthen immunity and resistance, and reduce the incidence of glomerulonephritis.