Oxygen is useful for pneumothorax because it compresses the lungs and if it is a large amount of pneumothorax, the patient will have difficulty in breathing, chest tightness and shortness of breath, which can be life-threatening in serious cases, so oxygen can relieve the patient’s symptoms of chest tightness and shortness of breath after giving oxygen. However, oxygen inhalation alone cannot solve the problem. Generally, pneumothorax that requires oxygen inhalation has a large pneumothorax volume and needs to be treated by thoracentesis or closed drainage of the chest cavity. The excess gas in the chest cavity will be expelled from the body, so that the lung will be reopened as soon as possible and the normal function of the lung will be restored in order to fundamentally cure the pneumothorax. This kind of pneumothorax usually requires thoracoscopic wedge resection of large lung blisters plus pleural fixation to avoid recurrence of pneumothorax.