More than 50 years ago it was thought that the cause of seborrheic dermatitis was an increase in endocrine androgens or elevated androgen receptors, and drugs that antagonize the effects of androgens were generally used, but the treatment has been unsatisfactory. The condition of high androgen levels exists for a long time in people, and female patients have to go through menopause syndrome before their hormone levels drop to a level that does not cause a rash, and male patients are about the same age The only way to avoid exacerbation at this time is to pay attention to lifestyle. In the last 5 years, we have found that seborrheic dermatitis is immune-related, and about 17% of patients can be transformed into undifferentiated connective tissue disease even after 3-5 years of development, which is an immune disease that can cause organ damage within the organism, so we are now taking a combination of drugs that antagonize the effects of androgens and immunotherapy for seborrheic dermatitis, and the results have improved significantly.