What to do about multiple ground glass nodules in both lungs

The presence of pulmonary ground glass nodules suggests a possible lung cancer, with special signs such as burr, lobulation, pleural wrinkling, bronchial inflation sign, etc. And even if it is lung cancer, most of them are early stage lung cancer. For suspected carcinoma, surgical resection is required. Bilateral pulmonary ground glass nodules can be completely removed surgically due to the location of the lesion growth and the constraints of the patient’s physical condition, but some patients cannot have all of them removed. If all nodules can be removed, the five-year postoperative survival rate of patients may reach 90% or 100% with reference to the most malignant ground glass nodules. If all nodules cannot be removed, the nodules most suspected of being malignant are removed first, while other nodules are observed for changes and further management is done when the physical condition improves. A pulmonary ground glass nodule is a focal well-defined hyperdense shadow in the lung on a chest CT scan that is ground glass-like, with insufficient density to obscure the bronchial vascular bundles traveling in it, and is classified as a pure ground glass nodule, a partially solid ground glass nodule, depending on whether it contains solid components. After review, the enlargement of ground glass-like nodules to more than 10 mm suggests possible malignant transformation to cancer, and partially solid nodules with ground glass-like shadowing solid component ≥6 mm may be early lung cancer.