Staying up late has an obvious effect on the heart rate. Staying up late can lead to an increase in the heart rate because the sympathetic nerves are overexcited when people stay up late, and the excitement of the sympathetic nerves can cause a rapid heart rate. In addition, the nerve, body fluid and endocrine system will also be affected when staying up late, which will activate the renin-angiotensin-aldosterone system and cause the patient’s blood pressure to increase and the heart rate to speed up. Staying up late also causes a significant decrease in coronary artery blood supply and increases the load on the coronary arteries and the heart, which can cause a rapid heart rate. So staying up late has an effect on the heart rate, and it can also cause significant cardiac insufficiency and overload of the heart, which can cause chronic heart failure.