Chest radiographs of both lungs with increased texture and multiple round-like nodular shadows may be caused by tuberculosis, bacterial lung abscess, lung cancer and other diseases, which need to be clarified after the specific cause of targeted treatment. 1. Tuberculosis: Tuberculosis is mainly related to the infection of tuberculosis bacillus, which can lead to the appearance of tuberculosis balls in the lungs of the patients, so that the patients will find thickening of lung texture and multiple round nodular shadows in the lungs, and need to take anti-tuberculosis drugs such as isoniazid, rifampicin and pyrazinamide under the guidance of doctors for the treatment. 2. Bacterial lung abscess: when bacterial infection leads to the formation of abscess in lungs, it can also lead to the increase of lung texture and round nodular shadows in lung films, which need to be actively treated with anti-infective therapy, and sensitive antibiotics can be used after examination to identify the pathogenic bacteria, and anti-infective medicines, such as cefuroxime tablets and amoxicillin capsules, etc., can be used in early stage according to the doctor’s instruction. 3. Lung cancer: Lung cancer and other lung tumors are also easy to make the patient’s two lungs texture thickening with multiple round nodules. Patients with this disease need to actively follow the doctor’s prescription for treatment, and the common treatment modes are surgery, chemotherapy and radiotherapy. Thickening of the texture of both lungs with multiple round-like nodular shadows on chest radiographs can be caused by a variety of diseases, and patients need to undergo further examination to make a clear diagnosis and then carry out targeted treatment.