Dry, rough and skinned feet is considered to be environmental factors, but can not exclude the possibility of eczema, tinea pedis and other diseases, the treatment needs to be based on the cause of the specific analysis, usually based on drug therapy. 1. Environmental factors: if the patient is in a dry environment for a long time, or in the dry season, the patient’s body lack of moisture is easy to appear feet dry and rough skinning, it is recommended that the patient to change the environment, as far as possible in a moist, comfortable environment, and at the same time you can apply some emollient to improve the skin condition, such as vitamin E milk. 2. Eczema: such as chronic eczema, the clinical will show dry and rough skin, the clinical generally take topical drugs, such as Dinocap, dexamethasone cream, tretinoin cream, etc., if the external drug control is not good, you can take antihistamines to relieve the symptoms of itching, such as loratadine tablets. 3. Tinea pedis: such as hyperkeratosis tinea pedis, there will be dry feet rough skin, clinical general use of medication, such as miconazole clobetasol cream, ketoconazole cream, amorphophallus hydrochloride cream, salicylic acid ointment and so on. If necessary, oral itraconazole can be combined. There may be other reasons for dry, rough and flaky feet, so it is recommended that patients seek medical attention to confirm the cause of the disease and then carry out targeted treatment. The above drugs need to be used under the guidance of a doctor.