Palmoplantar pustulosis generally refers to palmoplantar pustulosis. Palmoplantar pustulosis can be treated by medication, physical therapy and other methods. It is recommended that the patient go to the hospital in time, and choose the appropriate treatment plan under the judgment of the doctor. 1. Drug therapy: commonly used topical drugs such as glucocorticosteroids such as halometasone, but also can be used Vitamin A acid ointment, tacalcitol ointment or carbotriol ointment and so on. If necessary, it can be combined with oral retinoic acid drugs such as Avicenna, immunosuppressants such as cyclosporine, methotrexate and other drugs. 2. Physical therapy: commonly used in combination with ultraviolet A irradiation of the lesion area, irradiation of the lesion in the narrow-spectrum medium-wave ultraviolet radiation can also improve the symptoms of palmoplantar pustulosis. It is recommended that the patient go to the hospital in time, and follow the doctor’s instructions for medication.