Elevated blood glucose in ketoacidosis, most often diabetic ketoacidosis, can fall after insulin therapy, and the exact timing of the fall varies from person to person. Other types of ketoacidosis do not necessarily cause high blood sugar. The main causes of ketoacidosis include poor glycemic control in diabetic patients, alcoholism, starvation, and medications. The most common type of ketoacidosis is diabetic ketoacidosis, which is characterized by hyperglycemia, dehydration, and metabolic acidosis. Ketoacidosis is a common acute complication of diabetes mellitus, the patient’s body insulin is seriously insufficient, blood glucose is difficult to be absorbed and utilized, prompting lipolysis and metabolic capacity, and at the same time will generate a large number of ketone bodies, resulting in the accumulation of ketone bodies, leading to the occurrence of ketoacidosis. Patients with diabetic ketoacidosis will have high blood glucose values, usually at 16.7 to 33.3 mmol/L, and strong positive urine glucose and urine ketone bodies. After the onset of the disease, timely give rehydration, insulin supplementation and other treatments to control the rate of blood glucose decline of 3 to 5 mmol/L per hour, and closely observe the changes in the condition. At the same time, actively seek and eliminate the causative factors and treat complications. After the patient has ketoacidosis, he should go to the hospital in time to avoid delaying the condition and causing adverse consequences.