Treatment modes of centralized squamous lung cancer stage III include surgery, radiotherapy, chemotherapy, etc. The use of drugs should follow the doctor’s prescription. Centralized squamous lung cancer stage III belongs to middle and late stage, and the cancer cells have metastasized to mediastinum or extrapulmonary lymph nodes. 1. Surgery: some patients can be treated with chemotherapy first to reduce the lesion and lower the T and N stages, and then undergo surgery, such as thoracoscopic pneumonectomy. 2. Radiotherapy: palliative radiotherapy can inhibit the development of lung tumors, delay the spread of tumors, and relieve symptoms. 3. Chemotherapy: two-drug regimen combining third-generation chemotherapeutic drugs and platinum is the main first-line chemotherapy regimen, third-generation chemotherapeutic drugs such as paclitaxel and platinum drugs such as cisplatin. It is recommended that patients with centralized squamous lung cancer stage III go to regular hospitals and cooperate with professional doctors to further improve the quality of survival and maximize the survival period.