The redness, swelling and itching of the ankles may be related to insect bite dermatitis, contact dermatitis, eczema and other diseases, or rheumatoid arthritis, gout and other diseases. 1. Insect bite dermatitis is an allergic reaction caused by mosquito bites, which is clinically manifested by itching, redness, swelling, pimples, erythema and other phenomena, and the center of the lesions can be seen as obvious bite marks. 2. Contact dermatitis is due to local contact with some kind of goods and produce a perverse reaction, generally will be manifested as local skin redness, itching and swelling. 3. Eczema is due to a variety of internal and external factors that lead to skin diseases, in the clinical manifestations of more, generally itching-based, erythema, papule phenomenon. 4. Rheumatoid arthritis often violates some of the larger joints, so that the joints appear red, swollen, hot and painful phenomenon, some patients will have itching discomfort, the cause of the disease is mainly related to hemolytic streptococcal infection. 5. Gout in the clinic will also be manifested as some of the joints of the swelling and pain, due to the stimulation of inflammatory factors in some people can be accompanied by a slight itching discomfort, the cause of its onset is mainly related to hyperuricemia. The cause of the disease is mainly related to hyperuricemia. Due to the many factors involved in the development of the disease, it is necessary to consult a doctor and combine the results of laboratory tests to diagnose and treat the disease.