The paper sheet method drug sensitivity test is to stick the paper sheet impregnated with antimicrobial drug on the culture medium coated with bacteria according to certain requirements, measure the size of the circle of inhibition after cultivation for a period of time, and analyze the results according to the relevant interpretation standards, so as to draw a conclusion on the drug susceptibility of the subject strains of bacteria. In the paper method of drug sensitivity test, a certain amount of antimicrobial drugs will be absorbed into a specific piece of paper, and then placed on the solid culture medium that has been inoculated with the test bacteria, the drugs in the paper will diffuse outward by absorbing the moisture in the culture medium, inhibiting the growth of sensitive bacteria, thus resulting in the emergence of the ring of bacterial inhibition. As the drug spreads farther away, the lower the concentration of the drug that reaches that distance, so you can judge the sensitivity of the bacteria to the drug according to the size of the inhibition circle. Clinically, the paper slide drug sensitivity test is often used in acute and severe infections and mixed infections where the pathogenic bacteria have not yet been determined, as well as to delay the emergence of bacterial drug resistance. Because of the simple operation and easy to grasp characteristics of the paper slice drug sensitivity test, doctors often use the results of the drug sensitivity test to guide the clinical use of drugs. However, paper slice drug sensitivity test is only a kind of drug sensitivity qualitative test, in the experiment is susceptible to many factors, it is difficult to accurately determine the degree of bacterial sensitivity to drugs through the size of the inhibition circle. Therefore, the size of the circle of inhibition of the paper sensitivity test can not clearly reflect the sensitivity of a bacterium to drugs, not to mention the results of the paper sensitivity test can not be used to judge the sensitivity of bacteria to different drugs. The presence or absence or size of a drug’s inhibitory circle can only determine whether the drug has an effect on bacteria, and the sensitivity needs to be determined through scientific and strict experiments.