Alzheimer’s disease that is normal during the day and seems crazy at night is considered to be the result of severe damage to brain cell function in the advanced stages of Alzheimer’s disease. Alzheimer’s disease is commonly referred to as Alzheimer’s disease. In the advanced stage of Alzheimer’s disease (severe dementia stage), patients are prone to severe mental and behavioral abnormal symptoms. The patient is like a madman, with symptoms such as babbling, scolding others, excitement, irritability, etc. The above symptoms are especially obvious at night, which is caused by the severe impairment of brain cell function, and the patient’s day and night are reversed. Alzheimer’s disease is normal in the daytime but crazy at night. It is recommended that such patients go to the neurology department as early as possible to improve the imaging, blood and scale and other related examinations, so as to make a clear diagnosis and timely treatment, so as not to delay the condition.