LDL 4.34mmol/L is more serious. LDL normally does not exceed 3.37mmol/L, LDL 4.34mmol/L belongs to the LDL increase; elevated LDL is the key factor leading to the development of coronary heart disease and other atherosclerotic diseases. The main reason is that LDL will oxidize to form oxidatively modified LDL, and the oxidatively modified LDL triggers mutations in vascular endothelial cell function, thus triggering atherosclerosis; lowering the level of LDL can control and stop the oxidative process of LDL and prevent atherosclerosis. Commonly used LDL-lowering drugs include atorvastatin, pravastatin and other statins, which can lower LDL by accelerating the decomposition of LDL; they are not suitable for use in children, pregnant women, lactating women, and women preparing to give birth; adverse effects include elevated aminotransferases, myalgia, and myositis, and so on. Therefore, patients with LDL 4.34mmol/L should go to the hospital in time and choose the appropriate medication under the doctor’s guidance.