Whether chemotherapy is needed after 8 years of M5 leukemia depends on the patient’s condition; chemotherapy is needed if the condition is unstable and not needed if the condition is stable. Chemotherapy for M5 leukemia is divided into induced remission period, consolidation period and maintenance period. The first month of the disease is the induced remission period. If the treatment is stopped immediately after the disease is in remission, the leukemia will recur after a period of time. Therefore, it is necessary to consolidate the treatment, and the consolidation period usually takes 14 to 21 days. After the end of this period into the maintenance period, usually need 2 years. If after the three phases of treatment, the patient’s condition has been stable and has not recurred after regular checkups, chemotherapy may not be needed. If M5 leukemia has a tendency to recur after 8 years, it is recommended to go to the hospital for regular treatment under the guidance of a doctor. It should be noted that M5 leukemia patients can reduce the adverse effects of the disease through “early detection, early diagnosis, early treatment”, and some patients may survive for a long time, so it is recommended that patients establish confidence in treatment.