Sore throat followed by cold is commonly caused by cold and sore throat. If the symptoms are mild, no medication is needed; if the symptoms are severe, drugs such as cold and flu granules and compound aminophenolamine can be taken under the guidance of a physician to alleviate the discomfort. Sore throat can also be caused by acute pharyngitis, which can be treated with relevant medications. Colds are usually caused by viral infections induced by cold, fatigue and other factors, and can manifest as fever, sore throat, dry throat, cough and other symptoms, so the sore throat may be one of the symptoms caused by viral infections due to colds, rather than a sore throat followed by a cold. If the symptoms of sore throat are mild, the symptoms can be improved by drinking more water, paying attention to rest, and avoiding spicy food. If the symptoms are severe, medications such as cold and flu granules and compound aminophenol nanamin can be used to improve the discomfort of a sore and dry throat. Sore throat is not necessarily related to colds, such as caused by acute pharyngitis, can take compound borax solution gargle, watermelon cream throat tablets, etc. to relieve the symptoms, if necessary, can be given to the antiviral drugs such as viral azole, acyclovir and so on. If there is a basis for bacterial infection, antibiotics such as amoxicillin can be given to fight infection. Sore throat followed by cold may also be caused by other reasons, if the symptoms are not relieved or aggravated, it is recommended to consult a doctor in a timely manner to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.