If there is no drug resistance, prednisone has better efficacy in treating acute genitourinary tract infections caused by ureaplasma urealyticum. Ureaplasma urealyticum belongs to the genus Ureaplasma in Mycoplasma genitalium, for the treatment of its infection, it is best to take the secretion to do drug sensitivity test, and then according to the results of the drug sensitivity test to choose highly sensitive drug treatment, the effect is the best. If both men and women do not have symptoms related to genitourinary tract infections and are only infected with pathogens, they are considered carriers and do not need to be treated. If there are associated symptoms, antibiotics are used based on drug sensitivity tests. Mycoplasma is resistant to all antibiotics that act to inhibit cell wall synthesis and is sensitive to antibiotics that affect cell protein synthesis, including mainly tetracyclines, quinolones and macrolides. Doxycycline belongs to the semi-synthetic but hygromycin-derived tetracycline antibiotics, which are generally effective in treating Mycoplasma urealyticum. However, mycoplasma resistance to antibiotics is now more common, and doxycycline is not necessarily a sensitive drug for each individual mycoplasma infection. If resistance has developed, it is not effective. In diseases that are difficult to control with a single drug, a combination of 2 or 3 different types of antibiotics can help improve efficacy. Patients with mycoplasma infection should disinfect their clothes and washing utensils, etc. For daily necessities, it is important not to share them to avoid spreading the pathogen. Follow the doctor’s instructions for treatment, rather than unauthorized use of medication.