Neurological physical examination, cranial CT or magnetic resonance examination, and lumbar puncture cerebrospinal fluid laboratory examination are required for headache. 1. Physical examination of the nervous system: focusing on whether the mental state is clear, whether the function of higher nerves is normal, whether there is cerebral nerve paralysis, whether the neck is resistant, whether there is any sign of meningeal irritation, and the activity of the limbs, so as to roughly determine whether there is any intracranial lesion and the specific part of the brain tissue that may occur. 2. Cranial CT or magnetic resonance imaging (MRA): It is used to determine whether there are intracranial tumors, metastases, cerebral hemorrhage, cerebral infarction and other diseases. Doing a head CT or MRA can help find out if there is a brain aneurysm causing the headache. 3. Lumbar puncture: if headache is accompanied by fever and meningitis is suspected by CT scan, it is necessary to do lumbar puncture cerebrospinal fluid test to further clarify whether there is an intracranial infection and analyze whether it is caused by bacterial infection, viral infection or fungal infection. The symptoms of headache, need to consult a doctor in time, clear diagnosis and then targeted treatment.