If the patient is using dexamethasone for three days as prescribed by the doctor, there is usually no serious harm. Although dexamethasone is a glucocorticoid, prone to side effects, but in the therapeutic dose, the benefits generally outweigh the disadvantages, but the short-term application of large doses of dexamethasone can also make some people appear hormonal side effects: 1, folliculitis: some patients in the application of dexamethasone treatment, can appear hormone-induced folliculitis, boils and ulcer formation and other situations. It may turn into pustular papules and break down and overflow pus by itself, which is consistent with the performance of daily folliculitis and boils, and can be treated with antibiotics as prescribed by the doctor. 2. Gastric perforation: It is mainly seen in patients with underlying lesions of the stomach, and patients mostly have a long-term history of gastric ulcer. Dexamethasone and other glucocorticosteroids can damage the gastric mucosal barrier, and a large number of short-term applications for those without a history of ulcers may also cause some damage to the gastric mucosa; 3. Aseptic femoral necrosis: for some sensitive patients, short-term and large number of applications of dexamethasone may lead to the occurrence of the disease. It may manifest as hip pain and discomfort, and in severe cases, severe pain, femoral head subsidence and even walking difficulties may occur; 4. Hormonal atrophic striae: mainly seen in patients with long-term application of hormone therapy, and a few may also appear after short-term application of large doses of hormones. If the patient stops using dexamethasone after only three days, it will not happen, but if the patient continues to use it, there is a risk of atrophic lines. The dose and duration of dexamethasone use varies depending on the disease, so be sure to use the medication under the guidance of your doctor and avoid increasing or decreasing the dosage on your own. However, long-term use of high doses is likely to cause adverse reactions and lead to hyperadrenocorticism in the body, manifesting as full moon face, buffalo back, edema, hypertension and other symptoms.