The clinical manifestations of all liver diseases are almost identical in terms of the patient’s subjective perception. Moreover, these symptoms vary in severity and can range from abnormal liver function without any sensation to severe jaundice. On the other hand, there is no correlation between these symptoms and the severity of liver disease, and similar sensations can occur in either acute hepatitis or cirrhosis or liver cancer. Therefore, once typical liver disease symptoms appear, you should visit a liver specialist in person as early as possible to confirm the diagnosis through a detailed examination. Loss of appetite: Loss of appetite is one of the common symptoms of liver disease. If you lose your appetite for a long time, you should consider the possibility of hepatitis in addition to suspicion of gastritis and other diseases. Nausea, vomiting, abdominal distension: Many liver diseases are accompanied by nausea and vomiting, aversion to greasy food, and upper abdominal fullness after the development of abnormal liver function. Often patients are mistakenly seen for acute gastroenteritis, and experienced doctors will send patients for liver function tests to detect liver disease. Fatigue and weakness: In more severe cases of liver function abnormalities, there can be a lack of energy, laziness and low fever, much like having a “cold”. Some people may take cold medicine for a few days and go to the hospital only when they don’t get better. Liver palm: Liver palm is a specific manifestation of chronic liver injury, which is characterized by redness of the palms of the hands and fingertips, while the palms of the hands are white. This change can be seen in patients with various causes of chronic hepatitis, cirrhosis and liver cancer. Spider nevus: Spider nevus is a vascular nevus formed by branching dilatation at the end of small arteries in the skin, which resembles a spider, hence the name spider nevus. Spider nevi often appear on the face, neck, back of the hands, upper arms, forehead and shoulders. The diameter can range from the size of a pinhead to several centimeters or more. When the center of the nevus is pressed with a fingertip or cotton swab, the radial “network of small blood vessels” will fade and reappear after the pressure is removed. It is most common in patients with acute and chronic hepatitis or cirrhosis, but can also be seen in some patients with fatty liver. Jaundice: Jaundice is caused by an impaired metabolism of bilirubin in the body, resulting in an increased concentration of bilirubin in the blood, which leaks into the tissues and stains the sclera, mucous membranes and skin yellow. When a patient develops jaundice, he or she will show yellowing of the whites of the eyes, yellowing of the skin, and deepening of the color of the urine like overnight strong tea. The type of jaundice in severe liver disease is often hepatocellular, and this type of jaundice is often accompanied by symptoms such as weakness, lethargy, and loss of appetite.