“Fire” belongs to the category of heat syndrome in Chinese medicine, which can be seen in blisters on the mouth and other manifestations. Treatment requires the use of herbs that clear heat and fire (removing heat and fire from the body), and can be treated with Niu Huang Xie Du Toxin Tablets and Blue Scutellaria Oral Liquid. 1. Ox-huang Antidote Tablet: It contains artificial ox-huang, andrographis, gypsum, rhubarb and other ingredients, with the effect of clearing heat and detoxifying fire (removing heat and fire evil from the body). It is used for the internal exuberance of fire-heat, sore throat, swollen and painful gums, mouth and tongue sores, eye redness and swelling. The following adverse reactions can be seen: diarrhea, abdominal pain, nausea, gastrointestinal bleeding, dizziness, headache, palpitations (rapid heartbeat, often accompanied by panic), dyspnea and so on. Contraindicated in pregnant women, lactating women, infants and young children. It is forbidden for those who are allergic to this product and the ingredients contained in it. Caution is advised for those with weak spleen and stomach and loose stools. This product contains andrographis, should not be overdosed or taken for a long period of time, and should not be taken at the same time with other medicines containing andrographis. Caution should be exercised in patients with severe liver damage; caution should be exercised in patients with acute or chronic kidney disease. 2. Blue Scutellaria Oral Liquid: It has the efficacy of clearing away heat and removing toxins, relieving pharynx and eliminating swelling. It is used for acute pharyngitis, sore throat, dry throat and burning throat caused by solid heat syndrome of lung and stomach. Individual patients with mild diarrhea after taking the drug, usually can be relieved by themselves. Contraindications are not clear. It is not advisable to take warm tonic Chinese medicines at the same time during the period of taking the medicine. Caution should be exercised for those with wind-cold and cold sore throat, those with spleen deficiency and loose stools, and pregnant women. Avoid tobacco, alcohol, spicy, fishy food. Diabetic patients, children should be taken under the guidance of a physician. Allergic to the product is prohibited, allergic persons should be cautious. Blisters on the mouth on fire, it is recommended to consult a doctor, follow the doctor’s instructions to take medication, to avoid blindly use their own medication.