Colonic celiac bleeding spots are generally curable, if the immune system disorders caused by colitis, such as ulcerative colitis is not curable, but can be treated to control the speed of its bleeding as well as the progress of the disease. 1. The main cause of generalized colonic erosion and bleeding is that the intestinal flora loses its ability to regulate, resulting in persistent irritation of the intestinal tract, which leads to inflammation, ulceration, erosion, and bleeding. Patients usually have abdominal pain, abdominal distension, blood in stool and other symptoms, which can be cured by taking levofloxacin to sterilize and bismuth potassium citrate to protect the gastrointestinal mucosa. 2. Immune system disorders: If the immune system disorders caused by colonic erosion bleeding, such as ulcerative colitis is not curable, drug therapy can only control the progress of the disease, such as lorazosulfapyridine, mesalazine, to reduce the chances of erosion bleeding, if serious, feasible total colectomy plus ileal pouch anorectal anastomosis surgical treatment. Colonic erosion bleeding should go to the hospital in time for examination, to clarify what the specific cause is, targeted treatment, to avoid disease progression.