Kidney insufficiency grading in China used to be divided into 4 stages, compensated stage, decompensated stage, failure stage and uremic stage. Now they are all divided into CKD1-5 stages according to the American CKD staging, based on chronic kidneydisease (CKD). That is, it is divided into stages 1, 2, 3, 4 and 5. The staging criteria are based on the degree of damage to the glomerular filtration rate, and the glomerular filtration rate (GFR) is calculated based on the creatinine value in the kidney function combined with age and weight, and the higher the GFR, the better the kidneys can remove toxins. The value of staging can be recorded as 9-6-3-15, i.e. 90, 60, 30 and 15 staging criteria. The specific staging is as follows: Stage 1 Normal or elevated GFR with renal damage. GFR >902 stage Mildly decreased GFR with renal damage. GFR : 60 to 893 stage Moderate GFR decline. gfr : 30 to 594 stage Severe GFR decline. gfr : 15 to 295 stage Renal failure . gfr <15 or dialysis Renal insufficiency grading is based on chronic kidney disease (CKD) and is divided into CKD1-5 stages. Glomerular filtration rate (GFR) is calculated based on the creatinine value of kidney function combined with age and weight, and the higher the GFR, the better the kidneys can remove toxins. Renal insufficiency can be divided into four stages: Stage 1, renal function reserve compensatory stage. Because of the great compensatory capacity of the kidney reserve, although the kidney function is clinically reduced, its ability to excrete metabolites and regulate water and electrolyte balance can still meet the normal needs, and there are no clinical symptoms, and the kidney function tests are within the normal range or occasionally slightly higher. Stage II, renal insufficiency stage. The glomerulus has been damaged more, 60%-75%, the kidney excretion of metabolic waste has been somewhat impaired, creatinine urea nitrogen can be high or exceed the normal value. Patients can appear anemia, fatigue, weight loss, mental concentration, etc.. However, they are often neglected, but if there is water loss, infection, bleeding, etc., the symptoms will be obvious soon. The third stage, renal failure stage. The kidney function has been damaged quite severely, 75%-95%, can not maintain the stability of the body's internal environment, the patient is easy to fatigue, weakness, concentration and other symptoms increased, anemia is obvious, night urination increased, blood creatinine, urea nitrogen rose significantly, and often acidosis. This stage is also called the azotemia stage. Stage IV, uremic phase or end-stage renal insufficiency. In this stage, the glomerular damage has exceeded 95%, there are serious clinical symptoms, such as severe nausea, vomiting, low urine, swelling, pernicious hypertension, severe anemia, skin itching, urine smell in the mouth, etc. Chronic renal insufficiency is divided into 3 stages: 1, renal insufficiency compensatory stage: reduced glomerular filtration rate (GFR), endogenous creatinine clearance (Ccr) > 50ml/min; blood creatinine (Scr) ≤ 178μmol/L; blood urea nitrogen (BUN) ≤ 9mmol/L; generally no clinical symptoms of renal insufficiency. 2, renal insufficiency decompensation stage (azotemia stage): Ccr 25-50 ml/min; Scr>178μmol/L; BUN>9mmol/L; minor renal insufficiency symptoms: malaise, nausea, loss of appetite, anemia, etc. 3.Renal failure stage (uremic phase) Ccr＜25ml/min; Scr＞445μmol/L; BUN＞20mmol/L; water, electrolyte, acid-base balance disorder and obvious symptoms of each system appear. When Ccr <10ml/min, it is called end-stage uremia.