Only at night lying short of breath can not breathe, should improve the relevant examination to clarify the cause for targeted treatment. Sleep apnea syndrome, cardiac insufficiency, bronchial asthma and other diseases can lead to the symptoms of shortness of breath lying at night. 1. If sleep apnea syndrome is considered to be the cause, non-invasive ventilator can be worn to assist treatment, or consider nasopharyngeal surgery. 2. If cardiac insufficiency is considered to be the cause, cardiotonic diuretics such as furosemide, spironolactone, digoxin, and deacetyl furfuryl glycoside can be applied. 3. If considered for bronchial asthma, airway resistance increased due to, can be given to symptomatic asthma, relief of airway spasm medication, such as salbutamol, salmeterol, terbutaline, montelukast, aminophylline and so on. Only at night lying short of breath gasping for breath suggests that patients timely regular hospital cardiology, respiratory and other related departments, do not blindly use drugs. Improve the relevant examination to clarify the condition, under the guidance of professional physicians regular diagnosis and treatment.