Endocannabinoid, also known as mometasone furoate nasal spray, is a commonly used glucocorticosteroid drug with high bioavailability and can be used for children over the age of 3. Most children are generally unaffected by the use of endocannabinoids. Endocannabinoid is a glucocorticoid, the amount of topical medication absorbed into the body is small, generally follow the doctor’s instructions for regular use, for most children have no effect. A small number of children may experience localized nasal discomfort, such as nasal dryness and pain, nasal mucous membrane erosion, and repeated small amounts of nosebleeds, but the amount of bleeding is usually not large, and can be recovered on its own within 1-2 weeks after stopping the drug. Endocannabinoid hormone is widely used in the treatment of allergic rhinitis, chronic sinusitis, nasal polyps and other diseases, which can help reduce the sensitivity of the nasal mucosa, contract the nasal mucosa, improve nasal ventilation, and can also reduce the size of nasal polyps. The use of endocannabinoids after surgery for sinusitis and nasal polyps may also reduce the chance of recurrence. In addition, if the dryness of the nasal cavity is more obvious, it can be combined with the use of physiological seawater to clean the nasal cavity, which helps to keep the nasal cavity moist, and if the mucous membrane erosion of the nasal cavity is more obvious, it can be used with mucous membrane growth factors, such as topical application of recombinant human basic fibroblast growth factor. In addition, it is necessary to pay attention to avoid cold, away from allergens, as well as to ensure that the nasal cavity clean, is conducive to recovery.