Most myocardial bridges do not require treatment; some special cases require patient-specific drug selection. Coronary artery myocardial bridge refers to a special condition in which the trunk or branches of the coronary artery vessels on the surface of the heart travel beneath the myocardium, and most do not require treatment. As the heart contracts myocardial bridges compress the local coronary arteries to narrow, which may cause or aggravate myocardial ischemia, and in more serious cases, angina pectoris, myocardial infarction or even sudden death may occur, all of which require treatment. The purpose of myocardial bridge treatment is to reduce the compression of coronary arteries by myocardial bridges. For patients with symptomatic myocardial bridges, local myocardial bridge resection or coronary artery bypass grafting (bypass grafting) can be used, and stenting is generally not recommended for stenosis; patients with milder symptoms can also be treated with medications. The commonly used drugs are those that reduce myocardial ischemia by slowing down the heart rate and reducing oxygen consumption, including beta-blockers and non-dihydropyridine calcium antagonists (such as verapamil and diltiazem), etc. In addition, endothelial function damage and platelet aggregation are caused by coronary artery compression, so it is recommended to apply anti-platelet drugs. Patients with combined coronary artery disease are recommended to add statin lipid-lowering drugs. Most of the myocardial bridges do not require treatment, but if they cause severe myocardial ischemia, they need to be treated under the guidance of a doctor, and can be treated with beta-blockers, non-dihydropyridine calcium antagonists, or in more serious cases, surgery can be chosen.