The purpose of hysteroscopic endometrial biopsy is divided into the following situations: 1, postmenopausal elderly women: patients with vaginal bleeding, hysteroscopic biopsy can be used to clarify whether there are tumors or precancerous lesions; 2, patients with endometrial polyps: ultrasound shows that the endometrium is thickened to varying degrees or polypoid lesions, need to carry out an endometrial biopsy; 3, menopausal women: menstrual disorders, irregularities, excessive menstrual bleeding or prolonged menstruation, clinicians need to assess the situation of their uterine lining; 4, infertile people: failed to conceive for a number of times, the need to carry out a biopsy of endometrium, to determine the endometrium’s response to hormone conditions.