Five nights’ diarrhea (abdominal pain and desire for bowel movement before dawn) can be regulated by medication and acupuncture, with medication generally being the mainstay. 1. Medicines: Wujian diarrhea is generally caused by Yang deficiency of the spleen and kidney, so we can take Sishen Pills and Zhen Zhen Nourishing Viscera Soup to astringently stop diarrhea (to relieve diarrhea by enhancing the astringency of the intestinal tract) and warm up the spleen and kidney, but the use of medicines needs to go through the TCM doctor’s diagnosis. (1) Si Shen Wan: This medicine is mainly composed of Schisandra chinensis, Cornu Cervi Pantotrichum, and nutmeg, etc. It has the efficacy of astringing the intestines to stop diarrhea and warming and tonifying the spleen and kidney, and it can treat conditions such as diarrhea at the fifth night of the week caused by deficiency and coldness of the spleen and kidney, mental fatigue (mental exhaustion and physical weakness), and inability to think about food and drink, etc. This medicine is a classic formula for treating diarrhea at the fifth night of the week. The adverse reactions and contraindications of this medicine are not clear. (2) Zhen Zhen Nourishing Viscera Soup: This drug is mainly composed of Rhizoma Atractylodis Macrocephalae, Radix Panax Ginseng, Fructus Mucilaginae, Fructus Chebulae, Poppy Husk, etc. It has the efficacy of warming the spleen, warming the kidneys and astringing the intestines to stabilize detachment of the intestines and kidney to treat conditions of diarrhea, dysentery and detachment of the intestines and kidneys caused by prolonged yang deficiency of the spleen and kidney. The adverse reactions and contraindications of this drug are not clear; if the diarrhea is long, but the stagnation of dampness and heat has not gone, avoid using this prescription. 2. Acupuncture and moxibustion: Acupuncture and moxibustion can be applied to the spleen and kidney, kidney, Guanyuan, Vital gate, Sanyinjiao and other points to warm the spleen and kidney, astringe the intestines and stop diarrhea. Adverse effects such as dizziness and pain may occur after acupuncture; pregnant women and women during menstruation should be cautious of acupuncture. In addition, acupuncture should be performed by a professional TCM technician. If the above symptoms occur, it is recommended that the patient actively go to the hospital for consultation and treatment, do not self-medication or acupuncture operation, in order to avoid adverse consequences.